A controlled study of penfluridol in the treatment of chronic schizophrenia
Autor: | Lapierre Yd |
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Rok vydání: | 1978 |
Předmět: |
Adult
Male Fluphenazine medicine.medical_specialty business.industry Incidence (epidemiology) Middle Aged Penfluridol EMOTIONAL WITHDRAWAL Psychiatry and Mental health Piperidines Internal medicine Chronic Disease Toxicity Ambulatory Care Schizophrenia medicine Humans Female Chronic schizophrenia business medicine.drug |
Zdroj: | American Journal of Psychiatry. 135:956-959 |
ISSN: | 1535-7228 0002-953X |
DOI: | 10.1176/ajp.135.8.956 |
Popis: | Twenty patients were treated with penfluridol and 21 with fluphenazine for a period of up to 1 year. Penfluridol, an oral neuroleptic administered weekly was as efficacious as fluphenazine administered twice daily and appeared to be superior to fluphenazine in improving emotional withdrawal and anergia. The low incidence of side effects and other signs of toxicity, coupled with an effective prophylactic activity, suggests that penfluridol is an important addition to our therapeutic armamentarium for the treatment of chronic schizophrenia. |
Databáze: | OpenAIRE |
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