A controlled study of penfluridol in the treatment of chronic schizophrenia

Autor: Lapierre Yd
Rok vydání: 1978
Předmět:
Zdroj: American Journal of Psychiatry. 135:956-959
ISSN: 1535-7228
0002-953X
DOI: 10.1176/ajp.135.8.956
Popis: Twenty patients were treated with penfluridol and 21 with fluphenazine for a period of up to 1 year. Penfluridol, an oral neuroleptic administered weekly was as efficacious as fluphenazine administered twice daily and appeared to be superior to fluphenazine in improving emotional withdrawal and anergia. The low incidence of side effects and other signs of toxicity, coupled with an effective prophylactic activity, suggests that penfluridol is an important addition to our therapeutic armamentarium for the treatment of chronic schizophrenia.
Databáze: OpenAIRE