Acute Stress Persistently Enhances Estrogen Levels in the Female Rat
| Autor: | Tracey J. Shors, Martin Paczynski, Jane Pickett, Gwendolyn Wood |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Physiology medicine.drug_class Conditioning Classical Context (language use) Rats Sprague-Dawley Behavioral Neuroscience chemistry.chemical_compound Basal (phylogenetics) Stress Physiological Corticosterone Internal medicine Adrenal Glands medicine Animals Progesterone Swimming Estrous cycle Electroshock Sex Characteristics Endocrine and Autonomic Systems Ovary Estrogens Rats Associative learning Psychiatry and Mental health Neuropsychology and Physiological Psychology Endocrinology chemistry Estrogen Acute Disease Female Psychology hormones hormone substitutes and hormone antagonists Glucocorticoid Hormone medicine.drug |
| Zdroj: | Stress. 3:163-171 |
| ISSN: | 1607-8888 1025-3890 |
| DOI: | 10.3109/10253899909001120 |
| Popis: | Here we tested whether exposure to either tailshock or swim stress alters ovarian hormone levels, estrogen and progesterone, in females and whether the effects are persistent. Adrenal hormone levels were also measured in males and females. Estradiol levels were elevated in unstressed females during proestrus relative to females in other stages of estrous, and exposure to the stressors enhanced estradiol beyond basal levels. For females stressed during diestrus 2, estradiol levels were elevated immediately after stressor cessation and up to 24 hrs. Exposure to tailshock, but not swim-stress, transiently enhanced progesterone in females stressed during the stage of proestrus and estrus. Glucocorticoid levels were elevated in response to both stressors and were supraelevated in females under both basal and stress conditions relative to males, particularly in blood from females exposed to acute swim stress. These results indicate that exposure to a relatively acute stressful event immediately and persistently enhances serum estradiol and are discussed in the context of reports that exposure to the same stressors immediately and persistently impairs associative learning in the female rat. |
| Databáze: | OpenAIRE |
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