Low glycaemic diet and metformin therapy: a new approach in male subjects with acne resistant to common treatments
Autor: | Giuseppe Monfrecola, Claudio Marasca, Antongiulio Faggiano, Rosanna Izzo, Gabriella Fabbrocini, Francesca Marciello, M. Del Prete, Marianna Donnarumma, Riccardo Savastano, A. Colao |
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Přispěvatelé: | Fabbrocini, Gabriella, Izzo, R, Faggiano, A, Del Prete, M, Donnarumma, M, Marasca, C, Marciello, F, Savastano, R, Monfrecola, Giuseppe, Colao, Annamaria |
Rok vydání: | 2015 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent Diet Reducing endocrine system diseases medicine.medical_treatment Dermatology Group B Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Insulin resistance Internal medicine Acne Vulgaris medicine Adjuvant therapy Humans Hypoglycemic Agents Insulin Young adult Acne business.industry nutritional and metabolic diseases medicine.disease Combined Modality Therapy Metformin Glucose Glycemic index Endocrinology Glycemic Index 030220 oncology & carcinogenesis Insulin Resistance business medicine.drug |
Zdroj: | Clinical and Experimental Dermatology. 41:38-42 |
ISSN: | 0307-6938 |
Popis: | Acne is a common and complex skin disease, with a very complex pathogenesis. Although in women the relationship between acne and insulin resistance is well known, in particular in women with PCOS, in males this relationship has been poorly investigated. In total, 20 subjects with an altered metabolic profile were considered for this study and randomized as follows: 10 patients were treated with metformin plus a hypocaloric diet for 6 months (group A), while 10 patients did not receive any treatment with metformin and were only followed up (group B). All patients of group A, after 6 months of metformin therapy, had a statistically significant improvement compared with patients in group B. Our study reveals the importance of diet and insulin resistance in acne pathogenesis, and underlines the possible use of metformin and diet as possible adjuvant therapy for male patients with acne. |
Databáze: | OpenAIRE |
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