| Popis: |
Additional file 2: Figure. S1. (a) Paired t-test revealed that all eight genes were significantly elevated in omental metastases compared with the corresponding primary ovarian tumors in the dataset GSE30587. (b) Four genes (POSTN, LUM, COL3A1, COL5A2) of the LMGS were remarkably elevated, while COL5A1 was significantly down-regulated in SKOV3-OM3 (subpopulations derived from omental tumors in guest mice of the parabiosis models, representing omental metastases generated through a hematogenous route), compared to SKOV3ip1 intraperitoneal injected to the host mice (representing the primary tumors) in the dataset GSE52999. (c) Genes of the LMGS were likely to form a biologically functional network based on PPI analysis. Primary OV: primary ovarian cancer samples, Metastatic OM: omental metastases of ovarian cancer. * P |
