Optical Quality Resorbable Calcium-Phosphate Glasses for Biophotonic Applications
| Autor: | Davide Janner, Daniel Milanese, Diego Pugliese, Nadia Giovanna Boetti |
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| Rok vydání: | 2021 |
| Předmět: |
Optical fiber
Materials science genetic structures Extrusion business.industry Time-domain Diffuse Optics eye diseases Optical quality Characterization (materials science) law.invention Fiber Bragg grating Bioresorbable Optical Fiber law Optoelectronics In-vivo Testing sense organs Calcium-phosphate Glass Photonics Fiber Bragg Grating business Optical filter Spectroscopy |
| Zdroj: | PoliTO Springer Series ISBN: 9783030857752 |
| DOI: | 10.1007/978-3-030-85776-9_7 |
| Popis: | Recently developed calcium-phosphate glass formulations are proposed in this chapter as a new class of materials for biomedical optics and photonics. The glasses have been designed and carefully prepared in our laboratory to be dissolvable in biological fluids while being optically transparent, mechanically reliable both in dry and humid environments, and suitable for both preform extrusion and fiber drawing. Optical fibers have been drawn from these glasses using our custom-made induction heated drawing tower and showed attenuation loss values from one to two orders of magnitude lower than the counterpart polymeric-based bioresorbable devices reported in literature. In addition, the optical fibers have been implanted in living rats for several weeks and no clinical signs of any adverse effect have been found. Results on the inscription and characterization of different types of fiber Bragg grating-based optical filters will be also shown, together with the demonstration of the suitability of the above-mentioned bioresorbable optical fibers for time-domain diffuse optical spectroscopy. |
| Databáze: | OpenAIRE |
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