Fertility of patients with polycystic ovary syndrome undergoing in vitro fertilization by age
| Autor: | Yu-Im Hwang, I.O. Song, Eung-Gi Min, Hye-Ok Kim, Sun-Wha Cha, Kwang-Moon Yang |
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| Rok vydání: | 2015 |
| Předmět: |
Infertility
Adult medicine.medical_specialty Pregnancy Rate media_common.quotation_subject medicine.medical_treatment Oocyte Retrieval 030209 endocrinology & metabolism Fertility Fertilization in Vitro 03 medical and health sciences 0302 clinical medicine Ovulation Induction Pregnancy Republic of Korea medicine Humans Birth Rate media_common Retrospective Studies Gynecology 030219 obstetrics & reproductive medicine In vitro fertilisation business.industry Female infertility Age Factors Pregnancy Outcome Obstetrics and Gynecology General Medicine Tubal factor infertility medicine.disease Embryo Transfer Polycystic ovary female genital diseases and pregnancy complications Pregnancy rate Female business Infertility Female Polycystic Ovary Syndrome |
| Zdroj: | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. 135(1) |
| ISSN: | 1879-3479 |
| Popis: | Objective To evaluate outcomes of in vitro fertilization (IVF) among patients with polycystic ovary syndrome (PCOS) by age. Methods In a retrospective study, data were retrieved for patients with PCOS (Rotterdam 2003 criteria) and individuals with tubal factor infertility who underwent IVF at a center in Seoul, South Korea, between January 2003 and August 2012. IVF outcomes were compared by age group (A: 30–32 years; B: 33–35 years; C: 36–38 years; D: 39–41 years). Results The analysis included 307 women with PCOS and 364 with tubal factor infertility. There was a significant difference between women with PCOS and those with tubal infertility factor in the live birth rate in group B (41.3% vs 28.6%, P = 0.038) and in group C (40.4% vs 15.1%, P = 0.002). Among women with PCOS, no significant differences in number of retrieved oocytes were observed between the age groups (18.8 ± 9.6, 19.1 ± 10.0, 17.7 ± 7.5, and 17.0 ± 13.8). However, the clinical pregnancy rate was significantly lower in group D than in group C (47.2% vs 18.8%, P = 0.042). Conclusion Fertility in patients with PCOS was maintained until age 38 years using IVF. Thereafter, the pregnancy rate decreased, although the number of oocytes retrieved by IVF remained stable. |
| Databáze: | OpenAIRE |
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