Efficacy and acceptability of interventions for co-occurring PTSD and SUD: A meta-analysis
| Autor: | Tracy L. Simpson, Simon B. Goldberg, Keren Lehavot, Sage E Hawn, Shannon M. Blakey, Debra Kaysen, Kendall C. Browne, Diana K N Louden, Aline Lott |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Substance-Related Disorders Psychological intervention Treatment retention Comorbidity Substance use disorder behavioral disciplines and activities Article law.invention Stress Disorders Post-Traumatic Randomized controlled trial Co occurring law mental disorders medicine Humans Psychiatry Cognitive Behavioral Therapy Posttraumatic stress disorder medicine.disease Substance abuse Psychiatry and Mental health Clinical Psychology Posttraumatic stress Meta-analysis Cognitive behavior therapy Randomized controlled trials Active treatment Psychology Meta analysis |
| Zdroj: | Journal of anxiety disorders |
| ISSN: | 1873-7897 0887-6185 |
| Popis: | Over the past 20 years, numerous treatments addressing comorbid Posttraumatic Stress Disorder (PTSD) and Substance Use Disorder (SUD) have been developed and tested. The current meta-analysis examined the efficacy and acceptability of the two central treatment types- trauma-focused and non-trauma-focused - compared with all comparators and with cognitive-behavioral manualized SUD treatments immediately post-treatment and at longest follow-up. Twenty-eight randomized clinical trials (N = 3247) were included. There were small to large within-group effects for all forms of active treatment (gs = 0.30-1.11). Trauma-focused but not non-trauma-focused treatments outperformed all comparators on PTSD outcomes at post-treatment. Neither trauma-focused nor non-trauma-focused treatment outperformed all comparators on SUD outcomes at post-treatment. Neither trauma- nor non-trauma-focused treatment outperformed manualized SUD treatments on PTSD outcomes at either time point. Manualized SUD treatments outperformed trauma-focused treatments on SUD outcomes at post-treatment and non-trauma-focused treatments on PTSD outcomes at follow-up. Regarding treatment retention, neither trauma-focused nor non-trauma-focused treatments significantly differed from all comparators or from manualized SUD treatments. Between-group results were largely unchanged in trim-and-fill analyses, but were not robust to fail-safe N. Few moderators were detected. Taken together, results suggest that trauma-focused, non-trauma-focused, and manualized SUD interventions are sound options for individuals with comorbid PTSD/SUD. |
| Databáze: | OpenAIRE |
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