Left Ventricular Assist Devices in Patients With End-Stage Heart Failure
| Autor: | Tomás Pineda, Ijaz A. Khan, Eladio Sánchez, Panayotis Fantidis, José Ramón González, Juan Antonio Corrales, Ibrahim Tarhini |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Cardiac function curve
medicine.medical_specialty medicine.medical_treatment Cardiac resynchronization therapy Extracorporeal Cardiac Resynchronization Therapy Ventricular Dysfunction Left Risk Factors Internal medicine medicine Humans In patient Heart Failure Heart transplantation Intra-Aortic Balloon Pumping business.industry Patient Selection Hemodynamics medicine.disease Transplantation Heart failure Cardiology Heart Transplantation Heart-Assist Devices Cardiology and Cardiovascular Medicine business Destination therapy |
| Zdroj: | Angiology. 65:861-868 |
| ISSN: | 1940-1574 0003-3197 |
| DOI: | 10.1177/0003319713518838 |
| Popis: | Encouraging results were obtained by using left ventricular assist devices (LVADs) in patients with end-stage heart failure (HF) that exhibits extremely high mortality and who were not candidates for heart transplantation. By using this so-called destination therapy (DT), a substantial percentage of these patients achieved sufficient improvement in cardiac function to permit the explantation of the device. The combination of mechanical and pharmacological therapy increased the frequency and durability of myocardial recovery as compared with other therapeutic approaches. Although cardiac transplantation, LVADs, and cardiac resynchronization therapy have provided a major advance in DT, their limitations stimulate the search for alternative therapies. We discuss the limitations of these 3 treatment options for end-stage HF. Also, we propose and discuss the possible advantages of a new intracorporeal procedure that works continuously as intraaortic balloon counterpulsation without an extracorporeal or intracorporeal computer-controlled mechanism. |
| Databáze: | OpenAIRE |
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