Long-term quality of life improvement after transcatheter aortic valve implantation
| Autor: | George Karavolias, Mazen Khouri, Panagiota Georgiadou, Vassilis Voudris, Lila Papadimitriou, Panagiota Kontodima, Anna Smirli, Theodore Troupis, Eftihia Sbarouni, Theodoros Xanthos |
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| Rok vydání: | 2011 |
| Předmět: |
Male
Cardiac Catheterization medicine.medical_specialty Logistic euroscore Time Factors Transcatheter aortic medicine.medical_treatment Prosthesis Quality of life Surveys and Questionnaires Internal medicine medicine Overall survival Humans In patient Postoperative Period Aged Retrospective Studies Aged 80 and over Heart Valve Prosthesis Implantation business.industry Retrospective cohort study Aortic Valve Stenosis Middle Aged medicine.disease Surgery Stenosis Treatment Outcome Quality of Life Cardiology Female Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | American Heart Journal. 162:232-237 |
| ISSN: | 0002-8703 |
| Popis: | Transcatheter aortic valve implantation (TAVI) is a novel therapeutic option for severe aortic stenosis in old patients with high surgical risk. The aim of this study was to assess changes in quality of life (QoL) along with functional status and late survival after this procedure.Thirty-six consecutive patients (80.5 ± 5.9 years, 21 men and 15 women) with a logistic Euroscore of 29.7 ± 13.7 underwent TAVI using the 18-Fr CoreValve prosthesis. Aortic valve prosthesis was inserted retrograde using a femoral or a subclavian arterial approach. QoL was evaluated by administering the Short Form 36 (SF-36) tool and the shorter SF-12 version 2 (SF-12v2) questionnaires before and 1-year after TAVI.TAVI was successfully performed in all patients. The estimated 1-year overall survival rate using Kaplan-Meier method was 68%. One-year follow-up also showed a marked improvement in echocardiographic parameters (peak gradient 76.2 ± 26.1 vs 15.4 ± 7.8 mm Hg, P.001; aortic valve area 0.7 ± 0.1 vs 2.6 ± 2.7 cm(2), P.001) with a significant change in New York Heart Association class (3 ± 0.7 vs 1.2 ± 0.4, P.001). Both preprocedural summary SF-36 and SF-12v12 physical and mental scores showed a significant improvement 1 year after TAVI (21.6 vs 46.7, P.001; 42.9 vs 55.2, P.001; 22 vs 48.9, P.001; 43.3 vs 52.2, P.001, respectively).Our results show a marked 1-year clinical benefit in functional status and physical and mental health in patients who underwent TAVI. |
| Databáze: | OpenAIRE |
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