H pyloriinfection and other risk factors associated with peptic ulcers in Turkish patients: A retrospective study
| Autor: | Ersan Sander, Nizamettin Bayyurt, M. Fatih Abasıyanık, Barik A. Salih |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Peptic Ulcer medicine.medical_specialty Adolescent Turkish Peptic Gastroenterology Helicobacter Infections Risk Factors Internal medicine Humans Medicine Aged Retrospective Studies Aged 80 and over Aspirin Ethanol Helicobacter pylori biology business.industry Anti-Inflammatory Agents Non-Steroidal Smoking Retrospective cohort study General Medicine Middle Aged H pylori infection biology.organism_classification humanities digestive system diseases language.human_language body regions Duodenal ulcer Gastritis language population characteristics Female medicine.symptom business Rapid Communication medicine.drug |
| Zdroj: | World Journal of Gastroenterology. 13:3245 |
| ISSN: | 1007-9327 |
| Popis: | To identify and evaluate the relative impact of H pylori infection and other risk factors on the occurrence of gastric ulcer (GU), duodenal ulcer (DU) and gastritis in Turkish patients.A total of 4471 patients (48.3% female) out of 4863 attended the Samatya hospital in Istanbul (June 1999-October 2003) were included. The records of H pylori status (CLO-test), endoscopic findings of GU, DU and gastritis, personal habits (smoking, alcohol intake) and medication [non-steroidal anti-inflammatory drugs (NSAIDs), aspirin intake] were analyzed using multi-way frequency analysis.We have found that GU in the presence of H pylori had significant association with aspirin (P=0.0001), alcohol (P=0.0090) and NSAIDs (P=0.0372). DU on the other hand had significant association with aspirin/smoking/NSAIDs (P=0.0259), aspirin/alcohol (P=0.0002) and aspirin/smoking (P=0.0233), also in the presence of H pylori. In the absence of H pylori GU had significant association with alcohol/NSAIDs (P=0.0431), and NSAIDs (P=0.0436). While DU in the absence of H pylori had significant association with smoking/alcohol/ NSAIDs (P=0.0013), aspirin/NSAIDs (P=0.0334), aspirin/alcohol (P=0.0360).In the presence of H pylori, aspirin, alcohol and NSAIDs intake act as an independent risk factors that had an augmenting impact on the occurrence of GU and only together on the occurrence of DU in Turkish patients. |
| Databáze: | OpenAIRE |
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