Correlation of neutrophil-to-lymphocyte ratio with the prognosis of non-ST-segment elevation in patients with acute coronary syndrome undergoing selective percutaneous coronary intervention
| Autor: | Juan Wang, Donglai Cao, Zhisong Wang, Leng Han |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Medicine (General) Neutrophils major cerebrovascular adverse event medicine.medical_treatment Angiotensin-Converting Enzyme Inhibitors 030204 cardiovascular system & hematology Biochemistry Ventricular Function Left 0302 clinical medicine ST segment 030212 general & internal medicine Lymphocytes Neutrophil-to-lymphocyte ratio Ejection fraction major cardiovascular event non-ST-elevation acute coronary syndrome left ventricular ejection fraction General Medicine Middle Aged Prognosis Treatment Outcome risk factor Cardiology Female medicine.medical_specialty Acute coronary syndrome 03 medical and health sciences Angiotensin Receptor Antagonists R5-920 Internal medicine medicine Humans In patient cardiovascular diseases Lymphocyte Count Neutrophil to lymphocyte ratio Risk factor Acute Coronary Syndrome Aged Retrospective Studies business.industry Biochemistry (medical) percutaneous coronary intervention Percutaneous coronary intervention Stroke Volume Cell Biology medicine.disease business Retrospective Clinical Research Report |
| Zdroj: | The Journal of International Medical Research Journal of International Medical Research, Vol 48 (2020) |
| ISSN: | 1473-2300 |
| Popis: | Objective We aimed to explore the relationship between neutrophil-to-lymphocyte ratio (NLR) at three timepoints and prognosis of patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) undergoing elective percutaneous coronary intervention (PCI) within 1 year of PCI. Methods This retrospective study enrolled 231 patients with NSTE-ACS who received PCI and were followed for 1 year after PCI. The study population was divided into major adverse cardiovascular and cerebrovascular events (MACE) and non-MACE groups. Results In total, 214 patients completed the 1-year follow-up; 32 patients (15.0%) had MACE and 182 (85.0%) had no MACE. The MACE and non-MACE groups differed significantly in age, preoperative neutrophil count, preoperative and postoperative NLR, proportion of three-vessel lesion disease, preoperative lymphocyte count, postoperative lymphocyte count within 24 hours, postoperative lymphocyte count over 24 hours, and left ventricular ejection fraction (LVEF). Multivariate logistic regression analysis showed that preoperative NLR, postoperative NLR within 24 hours, age, and LVEF values were independent risk factors for MACE in patients with NSTE-ACS after elective PCI. Conclusion Compared with preoperative NLR, postoperative NLR (within 24 hours) may have a stronger ability to predict the occurrence of MACE in NSTE-ACS patients within 1 year after elective PCI. |
| Databáze: | OpenAIRE |
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