Non-physiological Aortic Flow and Aortopathy in Adult Patients with Transposition of the Great Arteries after the Jatene Procedure: A Pilot Study Using Echo Planar 4D Flow MRI
| Autor: | Kei Inai, Yumi Shiina, Michinobu Nagao |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Aortic arch
Adult congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty medicine.medical_treatment Transposition of Great Vessels Population Pilot Projects Regurgitation (circulation) 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine.artery Internal medicine Ascending aorta medicine Humans Radiology Nuclear Medicine and imaging education Aorta education.field_of_study business.industry Blood flow Arteries Magnetic Resonance Imaging Great arteries cardiovascular system Cardiology Senning Procedure business 030217 neurology & neurosurgery Jatene procedure |
| Zdroj: | Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine. 20(4) |
| ISSN: | 1880-2206 |
| Popis: | Purpose Dilated aortic root and ascending aorta (AAO) with progressive aortic regurgitation is a well-known sequela after arterial switch operation (ASO) in adults with transposition of the great arteries (TGA). We aimed to quantitatively assess aortic flow profiles in adults with TGA after ASO (Jatene procedure with LeCompte maneuver) using echo planar imaging (EPI) 4D flow MRI. Methods Prospectively, 9 consecutive adults (30.2 ± 6.6 years) after ASO (Jatene operation with LeCompte technique), 13 consecutive adults (34.3 ± 7.2 years) after the atrial switch operation with Senning procedure, and 8 age-matched control patients, who underwent turbo field echo (TFE) EPI 4D flow MRI (average scan time of approximately 4 min), were enrolled. Results TGA after ASO showed a markedly dilated sinus of Valsalva, compared to TGA after atrial switch operation (26.6. ± 4.9 vs. 18.6. ± 1.5 mm/cm2). Vorticity, helicity, wall share stress (WSS), and energy loss (EL) in the aortic root and the AAO in TGA were greater than in the controls. Vorticity, helicity, WSS, and EL in the aortic root and the AAO were also greater in TGA after ASO than after atrial switch operation. More acute aortic arch angle correlated with greater vorticity of the aortic root, and the significant diameter ratio of the sinus of Valsalva and the AAO was relevant to greater vorticity, helicity, and EL in TGA after ASO. Conclusions A non-physiological blood flow pattern of the aortic root was identified in TGA adults after the ASO (Jatene procedure with LeCompte maneuver). Missing spiral looping of the great arteries and the unique structure after the Jatene procedure may play an adjunctive role in promoting aortopathy. The evaluation of aortic flow profile using EPI 4D flow MRI may be useful for risk stratification for aortopathy in this population. |
| Databáze: | OpenAIRE |
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