Influence of patients' characteristics and disease management on asthma control
| Autor: | S. Chretin, Eric Van Ganse, Yves Pacheco, Laurent Laforest, Geneviève Chamba, Jean Bousquet, Gilles Devouassoux, Gisele Bauguil |
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| Přispěvatelé: | Health Service and Performance Research (HESPER), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, laboratoire du sommeil, CHU Grenoble, Service des maladies respiratoires, Hospices Civils de Lyon (HCL), Recherche en épidémiologie et biostatistique, Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département pneumologie et addictologie [Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Arnaud de Villeneuve, Immunovirologie et polymorphisme génétique, Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN) |
| Rok vydání: | 2006 |
| Předmět: |
Male
Adult medicine.medical_specialty Adolescent Immunology Pharmacy Lower risk primary care 03 medical and health sciences Sex Factors 0302 clinical medicine Drug Therapy Internal medicine Control medicine sex Humans Immunology and Allergy Anti-Asthmatic Agents 030212 general & internal medicine Disease management (health) Medical prescription Retrospective Studies Asthma Observer Variation 2. Zero hunger therapy business.industry Smoking Disease Management Retrospective cohort study Odds ratio Middle Aged medicine.disease 3. Good health Logistic Models 030228 respiratory system Multivariate Analysis Combination Physical therapy Regression Analysis Drug Therapy Combination Female [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie business Body mass index |
| Zdroj: | Journal of Allergy and Clinical Immunology Journal of Allergy and Clinical Immunology, Elsevier, 2006, 117 (6), pp.1404--1410. ⟨10.1016/j.jaci.2006.03.007⟩ |
| ISSN: | 0091-6749 |
| DOI: | 10.1016/j.jaci.2006.03.007 |
| Popis: | International audience; BACKGROUND: Although asthma control is a major outcome in disease management, little is known about its determinants. OBJECTIVES: We sought to study the relationships between asthma control and patient characteristics or asthma management. METHODS: Asthmatic patients (age 18-50 years) who were regular customers of pharmacies and had a prescription for an antiasthma medication were recruited consecutively. Patients completed a questionnaire, which was complemented by computerized pharmacy records of previously dispensed medications. Asthma control (adequate/inadequate) was assessed with the Asthma Control Test. Determinants of asthma control were identified by means of multivariate logistic regression analysis. RESULTS: The mean age of the 1351 patients included was 36.8 years (SD, 9.8), and 55.8% were women. A minority of patients were considered to have had their symptoms adequately controlled. Smoking, female sex, and a body mass index of greater than 30 kg/m2 were all independent determinants of inadequate control. Compared with patients receiving inhaled corticosteroid monotherapy, those who were dispensed fixed combinations of inhaled corticosteroids and long-acting beta-agonists presented with a significantly lower risk of inadequate asthma control (odds ratio, 0.58; 95% CI, 0.35-0.96). CONCLUSION: Asthma control varied according to both the patients' characteristics and therapy. CLINICAL IMPLICATIONS: Our results strongly support the need to improve asthma control, especially in primary care and in women. A regular use of fixed controller combinations, helping patients to quit smoking, or addressing weight issues might contribute to improvement in asthma control. |
| Databáze: | OpenAIRE |
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