Blood pressure, plasma NPY and catecholamines during physical exercise in relation to menstrual cycle, ovariectomy, and estrogen replacement
| Autor: | H. Switalska, W. Januszewicz, M Elaffi, Jolanta Chodakowska, Zofia Zukowska-Grojec, B Wocial, Piotr Pruszczyk, J Lewandowski |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
endocrine system medicine.medical_specialty Epinephrine Physiology medicine.drug_class Ovariectomy media_common.quotation_subject Clinical Biochemistry Blood Pressure Physical exercise Luteal phase Biochemistry Norepinephrine Cellular and Molecular Neuroscience Endocrinology Stress Physiological Internal medicine Follicular phase polycyclic compounds medicine Humans Neuropeptide Y Gonadal Steroid Hormones Exercise Menstrual Cycle Menstrual cycle media_common Estrogen Replacement Therapy Neuropeptide Y receptor surgical procedures operative Cardiovascular Diseases Estrogen Catecholamine Ovariectomized rat Female Psychology hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Regulatory Peptides. :239-245 |
| ISSN: | 0167-0115 |
| Popis: | Some evidences indicate that the female sex hormones protect against the development of cardiovascular diseases. Modulation of sympathetic activity may be one of the possibilities. We investigated the influence of treadmill stress on blood pressure (BP) and plasma neuropeptide Y (NPY), norepinephrine (NE) and epinephrine (E) concentrations in 11 normotensive, menstruating women in the follicular (HWf) and luteal (HWl) phases and in eight ovariectomized women, before (OVX) and after estrogen supplementation (OVXe). Both at rest and during exercise there were no differences in BP between HWf and HWl and between OVX and OVXe. During stress BP was significantly lower in HWf and HWl than in OVX but not in OVXe. NPY did not differ significantly between the groups of women either at rest or during activity. We did not observe differences in resting and stimulated NE and E between HWf and HWl and between OVX and OVXe. Neither resting nor activated NE and E differed between the groups, except higher stimulated NE in OVX than in HWf. These results suggest that the female sex hormones may modulate the BP response to dynamic exercise. Our data support evidence that this influence may be exerted by circulating catecholamines and not by NPY. |
| Databáze: | OpenAIRE |
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