A community-based case–control study of prevalence and pattern of cognitive impairments in patients with epilepsy residing in South-Eastern Nigeria
| Autor: | E. O. Arinzechi, Paul O Nwani, Lasbrey A Asomugha, Uche Dimkpa, Kelechi O. Enwereji, Cosmas M. Nwosu, Olubunmi A. Ogunrin |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
cognition
medicine.medical_specialty praxis Prevalence Neurological disorder lcsh:RC321-571 030218 nuclear medicine & medical imaging memory 03 medical and health sciences Epilepsy 0302 clinical medicine medicine Dementia Attention Psychiatry lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Psychomotor learning language business.industry General Neuroscience Case-control study Cognition medicine.disease Cognitive test epilepsy Original Article Neurology (clinical) business 030217 neurology & neurosurgery Clinical psychology |
| Zdroj: | Journal of Neurosciences in Rural Practice Journal of Neurosciences in Rural Practice, Vol 07, Iss 03, Pp 405-411 (2016) |
| ISSN: | 0976-3155 0976-3147 |
| Popis: | Background: Epilepsy is the commonest neurological disorder encountered in Sub-Saharan Africa. The quality of life of patients with epilepsy (PWEs) is adversely affected by cognitive impairments. Aim: This study investigated the prevalence and pattern of cognitive impairments in PWE in Ukpo community located in a South-Eastern state in Nigeria using Community Screening Interview for Dementia (CSID) and a computer-assisted cognitive test battery (FePsy). Methods and Patients: Fifty-one PWEs were studied and compared with 51 age-, sex-and level of education-matched healthy controls. Diagnosis of epilepsy was confirmed clinically with eye-witness corroboration. Sociodemographic data and information on epilepsy variables were obtained with the aid of a questionnaire. Cognitive domains assessed include language, memory, orientation, attention, psychomotor speed and constructional praxis. Results: The prevalence rate of cognitive impairment using total CSID score was 19.6%. Analysis of CSID scores revealed significant impairment in language (17.6%), memory (29.4%), orientation (15.7%), attention (7.8%) and constructional praxis (15.7%) compared to healthy controls. A similar pattern was observed with FePsy but with better sensitivity indices for detecting cognitive impairment. Conclusion: This study indicated significant prevalence rate of cognitive impairment among treatment-naïve PWE with profound affectation of memory, mental speed and language. In addition, the FePsy was found to be more sensitive and specific in assessment of cognitive function in PWE. |
| Databáze: | OpenAIRE |
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