LOCAL CONTROL OF PROSTATE CANCER BY TRANSRECTAL HIGH INTENSITY FOCUSED ULTRASOUND THERAPY: PRELIMINARY RESULTS
| Autor: | Raymonde Bouvier, Jean-Yves Chapelon, C. Pangaud, Y. Lasne, Albert Gelet |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
business.industry Prostatectomy Urology medicine.medical_treatment Ultrasound medicine.disease High-intensity focused ultrasound Surgery Prostate-specific antigen Prostate cancer medicine.anatomical_structure Prostate Medicine Adenocarcinoma Histopathology business Nuclear medicine |
| Zdroj: | Journal of Urology. 161:156-162 |
| ISSN: | 1527-3792 0022-5347 |
| DOI: | 10.1016/s0022-5347(01)62087-1 |
| Popis: | Purpose: We conducted a phase I/II study to evaluate the efficacy of transrectal high intensity focused ultrasound in the treatment of localized prostate cancer and to assess associated complications. The efficacy of a new high intensity ultrasound device was evaluated using posttreatment prostate specific antigen (PSA) levels and histological results from prostate biopsies as end points.Materials and Methods: A total of 113 transrectal high intensity focused ultrasound sessions were performed in 50 patients with localized prostate cancer, who were not suitable candidates for radical prostatectomy. Of these patients 2 underwent salvage ultrasound treatment for locally recurrent cancer following definitive radiation therapy. Mean plus or minus standard deviation patient age, PSA and prostate volume were 70.7 +/− 4.54 years, 9.61 +/− 7.42 ng./ml. and 37.3 +/− 19.1 cc. The 2 different high intensity ultrasound prototypes were successfully used, and the latter prototype included several safety devices... |
| Databáze: | OpenAIRE |
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