Lipid-based Nanocarriers for Cancer and Tumor Treatment
| Autor: | M. Saquib Hasnain, Thiya Anissa Ramlan, Nurul Nadia Jamaluddin, Shahnaz Majeed, Abdullah Khan, Farheen Sami, Roshan Salfi, Nurshahiera Zamri, Mohammed Tahir Ansari |
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| Rok vydání: | 2020 |
| Předmět: |
Drug
media_common.quotation_subject medicine.medical_treatment 01 natural sciences 03 medical and health sciences Drug Delivery Systems Neoplasms Drug Discovery medicine Humans 030304 developmental biology media_common Pharmacology 0303 health sciences Chemotherapy Liposome Drug Carriers business.industry Cancer medicine.disease Lipids 0104 chemical sciences 010404 medicinal & biomolecular chemistry Targeted drug delivery Drug delivery Cancer cell Cancer research Nanoparticles Nanocarriers business |
| Zdroj: | Current pharmaceutical design. 26(34) |
| ISSN: | 1873-4286 |
| Popis: | Cancer and tumor have been major reasons for numerous deaths in this century across the world. Many strategies have been designed to treat, diagnose, or prevent cancer. The success of chemotherapy largely depends on drug targeting. The advent of nanotechnology has vastly improved drug delivery for targeting and diagnosis. Nevertheless, the accuracy of drug targeting with polymeric nanoparticles has always been questionable. The polymeric nanoparticles synthesized from varieties of lipid-based compounds or combined with vectors, such as liposomes, ethosomes, and transfersomes, may allow the drug to overcome the issue of resistance to drug absorption in biological membranes. The combined effects of lipid-based nanocarriers are known to improve the efficacy and accuracy of polymeric nanoparticles. The present review explores the application of lipid based nanocarriers in the treatment and diagnosis of cancer A special focus is given to the use of lipid-based nanocarriers in the treatment, diagnosis, and mitigation of cancer located in blood, brain, lung, and colon. The treatment of these cancers has always been questionable as the chances of relapse are very high. The review encompasses the use of lipid-based nanocarriers in targeting tissue-specific cancer cells. |
| Databáze: | OpenAIRE |
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