Fractal analysis of mucosal microvascular patterns in oral lichen planus: a preliminary study
| Autor: | Enrica Gentile, Gionata De Vico, Gabriel Landini, Alberta Lucchese, Rosario Serpico, Giovanni Capone |
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| Přispěvatelé: | Lucchese, Alberta, Gentile, Enrica, Capone, Giovanni, DE VICO, Gionata, Serpico, Rosario, Landini, Gabriel, Gentile, E, Capone, G, De Vico, G, Landini, G. |
| Rok vydání: | 2015 |
| Předmět: |
Male
Pathology medicine.medical_specialty Vascular architecture Pathology and Forensic Medicine stomatognathic system Tongue Oral and maxillofacial pathology medicine Humans Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Oral mucosa Aged business.industry Microcirculation Mouth Mucosa Buccal administration Middle Aged medicine.disease Fractal analysis stomatognathic diseases Fractals medicine.anatomical_structure Close relationship Surgery Oral lichen planus Oral Surgery business Lichen Planus Oral |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 120:609-615 |
| ISSN: | 2212-4403 |
| Popis: | Objectives The objective of this study was to assess local vascular architecture in atrophic-erosive oral lichen planus (OLP). Materials and Methods We investigated the capillary structure of the oral mucosa in 31 patients with OLP and 32 healthy controls. Capillaries images were captured in vivo through a capillaroscope. We applied fractal analysis to quantify the microvasculature morphometric changes in the oral mucosa of atrophic-erosive OLP patients in terms of their fractal dimension (D). Results The oral vascular networks of atrophic-erosive OLP lesions had a significantly higher D, both in buccal mucosae (D = 1.167, P = .019) and in tongue (D = 1.196, P = .038), compared with the control population (1.123 for both locations, respectively). Conclusions The present study confirms previous literature data on a close relationship between abnormal vascular architecture and atrophic-erosive OLP. Fractal analysis provided a quantitative descriptor of the complexity of the vascular patterns, which increases in the OLP samples. These data may provide new information on the OLP pathogenesis, as well as serve as morphologic quantifiers for monitoring treatment strategies. |
| Databáze: | OpenAIRE |
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