Antimicrobial Potential of Microorganisms Isolated from the Bottom Sediments of Lake Baikal
| Autor: | Valery Pavsky, Veronika Anohova, Stanislav Sukhikh, Margarita A. Shevchenko, Evgeny Chupakhin, Svetlana Noskova, Maria Zimina, Olga Babich, Svetlana Ivanova |
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| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
Microorganism genetic identification Bacillus Micrococcus RM1-950 Biochemistry Microbiology Article 03 medical and health sciences bottom sediments Bacteriocin Pharmacology (medical) Microbial mat General Pharmacology Toxicology and Pharmaceutics Lake Baikal metabolites 030304 developmental biology 0303 health sciences antimicrobial activity biology 030306 microbiology Pseudomonas extremophilic microorganisms biology.organism_classification Antimicrobial Pseudomonas putida Infectious Diseases Therapeutics. Pharmacology |
| Zdroj: | Antibiotics Volume 10 Issue 8 Antibiotics, Vol 10, Iss 927, p 927 (2021) |
| ISSN: | 2079-6382 |
| Popis: | Extremophilic microorganisms attract researchers by their unique characteristics, primarily antagonistic ones, acquired in the process of survival in extreme natural conditions. The antimicrobial potential of the metabolites of these microorganisms is quite broad, from the food industry to therapeutic drugs. Microbial mats of Lake Baikal are a source of unique and diverse microorganisms. The study aimed to evaluate the antimicrobial activity of bacterial strains isolated from the bottom sediments of the lake. Using heterotrophic growth conditions, seven bacterial strains were isolated from samples collected in several coastal zones of Lake Baikal. Thisstudy identified both widespread strains of the genera Pseudomonas and Bacillus and rare genera Micrococcus and Acinetobacterrepresentatives. Metabolites of five strains were found to have a broad spectrum of antimicrobial activity. Four large fractions of metabolites of the isolated strains wereidentified. Two peptides of the isolated fractions of metabolites (one is produced by microorganisms of all five isolated strains, another—only by Pseudomonas putida) are low molecular weight oligopeptides. These peptides were proved to be bacteriocins. |
| Databáze: | OpenAIRE |
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