Fumonisins B1 + B2 change the expression of genes in apoptosis balance in Nile tilapia fingerlings
| Autor: | Natália H.A.P. Mora, C.S. Nascimento, Eliane Gasparino, Stefânia C. Claudino-Silva, V. V. Pereira, Bruno Lala, Christiano Rodrigues Schamber, Dayne Loraine Hedler |
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| Přispěvatelé: | University Center of Maringá, Universidade Estadual Paulista (Unesp), Faculdades Unidas do Vale do Araguaia, Universidade Estadual de Maringá (UEM), Universidade Federal de Sergipe (UFS), Faculdade Pitágoras, PROBIC Scholarship |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Messenger RNA Mycotoxin food.ingredient Fumonisin Oreochromis niloticus Tilapia Aquatic Science Biology biology.organism_classification humanities 03 medical and health sciences chemistry.chemical_compound Nile tilapia 030104 developmental biology food chemistry Apoptosis Gene expression Ingestion Food science |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| Popis: | Made available in DSpace on 2018-12-11T16:51:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-03-10 In this study, we tested the hypothesis that the ingestion of feed containing fumonisin affects the apoptosis balance in liver cells. Thus, a trial was conducted with Nile tilapia fingerlings (2.64 ± 0.06 g) fed diets containing increasing levels of fumonisin (FB) (0-control diet, 20, 40, and 60 mg/kg), and expression of caspase7 (CASP7) and sphingosine phosphate lyase (SPL) genes in liver tissue was evaluated at 15 and 30 days of treatment. SPL:CASP7 mRNA ratio was also evaluated. Relative mRNA levels of SPL decreased in tilapia treated with 60 mg FB/kg of diet at 15 days (P |
| Databáze: | OpenAIRE |
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