Supplementary Revised Figure S1 from MUC16 Regulates TSPYL5 for Lung Cancer Cell Growth and Chemoresistance by Suppressing p53

Autor:	Apar Kishor Ganti, Surinder K. Batra, Moorthy P. Ponnusamy, Subodh M. Lele, Raghupathy Vengoji, Rama Krishna Nimmakayala, Prabin D. Majhi, Srustidhar Das, Abigail Thomas, Satyanarayana Rachagani, Parthasarathy Seshacharyulu, Shereen Salfity, Imayavaramban Lakshmanan
Rok vydání:	2023
Popis:	MUC16 incidence in lung cancer. A, MUC16 is overexpressed in a greater proportion of lung adenocarcinoma compared to other histological subtypes. B, Data from TCGA also shows that MUC16 is highly expressed in adenocarcinoma tissues than squamous carcinoma tissues. C, TSPYL5 transcript was significantly decreased in MUC16 knockdown (H292-shMUC16 seq1 and shMUC16 seq2) as validated by quantitative real-time PCR analysis. D, Immunoprecipitation assay demonstrated that STAT3 interacts with GR in lung cancer cells. **P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20142af2ff59959be7cd34aab7c53b41 https://doi.org/10.1158/1078-0432.22465764 Zobrazit plný text záznamu