Subclinical entheseal involvement in patients with rheumatoid arthritis
| Autor: | Asmaa M. AbdEllah, Rasha M. Hamouda, Maryam A. Abdulrahman, Reem A. Habeeb, Adel Mahmoud El Sayed, Safaa A. Hussein |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Visual analogue scale 03 medical and health sciences 0302 clinical medicine Rheumatology Internal medicine medicine Enthesitis 030212 general & internal medicine Disease activity Rheumatoid arthritis Subclinical infection 030203 arthritis & rheumatology medicine.diagnostic_test business.industry Enthesopathy Magnetic resonance imaging RC581-607 medicine.disease GUESS medicine.anatomical_structure Musculoskeletal ultrasound Ankle medicine.symptom Immunologic diseases. Allergy business Rheumatism |
| Zdroj: | Egyptian Rheumatologist, Vol 43, Iss 4, Pp 281-286 (2021) |
| ISSN: | 1110-1164 |
| Popis: | Background Enthesopathy is a common feature of Spondyloarthritis (SpA) but can also be found in rheumatoid Arthritis (RA). Recognizing enthesopathy could be challenging because of low sensitivity and specific clinical testing. To detect enthesopathy, The European League Against Rheumatism (EULAR) recommends magnetic resonance imaging (MRI) or ultrasonography (US). Aim of the work To investigate the frequency and distribution of entheseal involvement in RA patients and its relation to disease activity. Patients and methods 100 RA patients with any symptom in foot and ankle were enrolled. Disease activity score (DAS28), Visual analogue scale (VAS), Health assessment questionnaire-Disability index (HAQ-DI) and Glasgow Ultrasound Enthesitis Scoring System (GUESS) were assessed. Results The mean age of patients was 44.1 ± 12.2 years, disease duration was 7 ± 5.8 years and 86% were females. The mean DAS28 score was 4.3 ± 1.2 and GUESS score was 7.2 ± 4.2; all patients had variable degrees of enthesitis: 30% of patients had mild enthesitis, 42% had moderate enthesitis and 28% had marked enthesitis. GUESS was significantly higher in patients with moderate (7.8 ± 4.9) and high (7.2 ± 3.2) disease activity than in patients with low disease activity (5.2 ± 3.9) and those in remission (6.5 ± 1.9) (p = 0.015). HAQ, Age and ESR significantly correlated with GUESS score (r = 0.19, p = 0.049; r = 0.23, p = 0.023; r = 0.33, p = 0.001 respectively). Conclusion Subclinical enthesitis is remarkable in RA patients. Quadriceps tendon enthesis was mostly affected. Enthesitis is significantly related to age, ESR and HAQ. The presence of enthesitis in RA may represent a potential marker for disease activity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect