Synthesis, spectroscopic characterization and antimicrobial activity evaluation of new tridentate Schiff bases and their Co(II) complexes
| Autor: | Darshana Raut, K. Aruna, Ganesh More, Sakina Bootwala |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Schiff base
010405 organic chemistry Stereochemistry Ligand Monobasic acid General Chemistry bacterial infections and mycoses 010402 general chemistry Antimicrobial 01 natural sciences Magnetic susceptibility 0104 chemical sciences lcsh:Chemistry Metal chemistry.chemical_compound lcsh:QD1-999 chemistry visual_art Polymer chemistry Octahedral molecular geometry visual_art.visual_art_medium Stoichiometry |
| Zdroj: | Journal of Saudi Chemical Society, Vol 21, Iss 8, Pp 954-964 (2017) |
| ISSN: | 1319-6103 |
| DOI: | 10.1016/j.jscs.2017.05.002 |
| Popis: | A series of Schiff base tridentate ligands and their respective Co(II) complexes have been synthesized and characterized by elemental analysis, magnetic susceptibility, IR, NMR and UVâVisible spectra, thermal studies. The IR spectral data suggested that all the ligands acted as monobasic tridentate towards central Co(II) ion with an ONO donor atoms sequentially. Analytical data and magnetic susceptibility revealed 1:2 metal to ligand stoichiometry and octahedral geometry for all Co(II) complexes. All the prepared compounds were also screened for antimicrobial activity against 5 ESBL (Extended Spectrum β-lactamase) and 5 MBL (Metallo β-lactamase) producing uropathogens and for antitubercular activity against Mycobacterium tuberculosis (H37Rv strain). Keywords: Schiff base, Antitubercular, Antimicrobial, ESBL, MBL, Metal complex, o-hydroxyl aldehyde, Aminothiophene |
| Databáze: | OpenAIRE |
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