Effectiveness of Minimally Invasive Hybrid Surgery for Ileal Interposition (MIHSII) for the Resolution of Type 2 Diabetes
| Autor: | Vani Krishna, Farish Shams, Anithadevi T S, Sulfia P. J, Shaji P.G, Padmakumar Ramakrishnapillai, Praveen Kumar, Madhukara Pai |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Sleeve gastrectomy medicine.medical_treatment Population 030209 endocrinology & metabolism Type 2 diabetes Extracorporeal 03 medical and health sciences 0302 clinical medicine Gastrectomy Ileum Diabetes mellitus medicine Humans education Aged Retrospective Studies Glycated Hemoglobin education.field_of_study business.industry Insulin Middle Aged medicine.disease Surgery Image-guided surgery Diabetes Mellitus Type 2 030211 gastroenterology & hepatology Female Laparoscopy business Body mass index |
| Zdroj: | Surgical innovation. 23(1) |
| ISSN: | 1553-3514 |
| Popis: | Aim. To evaluate the effectiveness of minimally invasive hybrid surgery for ileal interposition (MIHSII), a novel procedure for type 2 diabetes (T2DM) in patients with a body mass index (BMI) 2. Materials and methods. MIHSII is an innovative technique in which sleeve gastrectomy is performed laparoscopically, followed by extracorporeal ileal interposition performed through a 5-cm midline incision. The procedure was performed on 31 T2DM patients, 17 males and 14 females. Their BMI values ranged from 21.8 kg/m2 to 29.8 kg/m2, with a mean BMI of 26.61 ± 2.61 kg/m2. The average duration of diabetes 8.14 ± 4.89 (range = 1-20) years. Most of the patients exhibited poorly controlled diabetes despite the use of oral hypoglycemic agents (OHAs) and/or insulin. Results. The mean preoperative glycosylated hemoglobin (HbA1c) for the population was 8.86%. The mean HbA1c 1 year after surgery was 6.80%. The difference between the mean preoperative and 1-year postoperative HbA1c values was significant, at P < .05 (group 1: BMI = 18.5-24.99 kg/m2, t = 2.83, and P = .022; group 2: BMI = 25-29.99 kg/m2, t = 4.23, and P = .001). The resolution rate of diabetes was 80.48%; 48.57% experienced complete resolution, and 31.91% experienced partial resolution. The remaining 19.52% of patients exhibited a significant reduction in HbA1c, although the HbA1c levels did not fall below 6.5%, even with medications. Conclusion. MIHSII is an innovative technique of metabolic surgery and is a cost-effective and minimal procedure for the resolution of T2DM in patients with BMI 2. |
| Databáze: | OpenAIRE |
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