A Study on the Clinical and Angiographic Spectrum of Spontaneous Extracranial Dissections in the Cerebral Vasculature
| Autor: | R.K. Anadure, Rajeev Sivasankar, Aneesh Mohimen, Rajeev Saxena |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
heparin Magnetic resonance angiography lcsh:RC321-571 03 medical and health sciences 0302 clinical medicine Modified Rankin Scale medicine angiography cardiovascular diseases 030212 general & internal medicine lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Stroke cerebral dissections Computed tomography angiography medicine.diagnostic_test Arterial dissection business.industry General Neuroscience medicine.disease Dissection Angiography Etiology Original Article Neurology (clinical) Radiology business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Neurosciences in Rural Practice, Vol 09, Iss 03, Pp 344-349 (2018) Journal of Neurosciences in Rural Practice |
| ISSN: | 0976-3155 0976-3147 |
| Popis: | Aim: To prospectively study the clinical profile, angiographic features, and functional outcomes, in consecutive cases of extracranial dissection seen at two tertiary stroke care centers in South India. Materials and Methods: In this observational study, spanning 4 years (December 12–December 16), a total of 442 patients presented with an acute ischemic stroke/transient ischemic attack (TIA) at our study centers. 14/546 (3.2%) of these patients had magnetic resonance angiography (MRA)/computed tomography angiography (CTA) evidence of extracranial dissections. All cases underwent detailed clinical evaluation on arrival, and data were recorded on a predesigned stroke pro forma. Contrast MRA was done on arrival in all cases as part of a standard stroke protocol, and CTA was done only if MRA was inconclusive. The pattern of the vessel involved and morphology of vessel dissection was analyzed as per a standard radiology protocol. All the cases were managed with short-term anticoagulation using low-molecular-weight heparin followed by oral anticoagulants for 3–6 months. All cases were followed up for 1–2 years and the functional outcomes were recorded using the modified Rankin Scale (mRS). Results: There were 11 males and 3 females in the study, and the mean age was 45.1 years (range = 27–65 years). Focal neurological symptoms occurred in all these patients (10 patients had a stroke, and 4 had TIA). Nearly 64.2% of these (9/14) were stroke in young (age |
| Databáze: | OpenAIRE |
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