Intrauterine growth retardation in renal insufficiency: An experimental model in the rat
| Autor: | Joseph D. Schulman, Barbara L. Chrzanowska, Menachem Nitzan, Sheldon Orloff |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Food intake
medicine.medical_specialty Pregnancy Trimester Third Disease Nephrectomy Eating Pregnancy Internal medicine Animals Medicine Maternal undernutrition Vascular insufficiency Uremia Fetal Growth Retardation Growth retardation business.industry Experimental model Body Weight Obstetrics and Gynecology medicine.disease Rats Pregnancy Complications Disease Models Animal Endocrinology Kidney Failure Chronic Gestation Female business |
| Zdroj: | American Journal of Obstetrics and Gynecology. 133:40-43 |
| ISSN: | 0002-9378 |
| DOI: | 10.1016/0002-9378(79)90408-3 |
| Popis: | Experiments described here with partially nephrectomized pregnant rats with pair-fed controls and controls fed at will indicate that decreased maternal food intake is a major factor in the intrauterine growth retardation associated with moderate renal insufficiency during the last trimester of gestation. Although renal disease in human pregnancy is often associated with vascular insufficiency, the possibility that maternal undernutrition may also play a contributory role in the fetal growth failure associated with certain cases of human renal compromise merits further study. |
| Databáze: | OpenAIRE |
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