Evaluating and comparing the image quality and quantification accuracy of SiPM-PET/CT and PMT-PET/CT
| Autor: | Yuji Tsutsui, Shinichi Awamoto, Toyoyuki Kato, Kazuhiko Himuro, Shingo Baba, Masayuki Sasaki |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Quality Control Scanner Image quality Standardized uptake value Sensitivity and Specificity Imaging phantom 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Silicon photomultiplier Fluorodeoxyglucose F18 Positron Emission Tomography Computed Tomography Image Processing Computer-Assisted Medicine Humans Radiology Nuclear Medicine and imaging Retrospective Studies PET-CT business.industry Phantoms Imaging General Medicine Visual score 030220 oncology & carcinogenesis Female business Nuclear medicine |
| Zdroj: | Annals of nuclear medicine. 34(10) |
| ISSN: | 1864-6433 |
| Popis: | The aim of this study was to evaluate the image quality and the quantification accuracy of Biograph Vision PET/CT scanner as a SiPM-PET in comparison to the conventional PMT-PET, Biograph mCT PET/CT scanner. This study consisted of a phantom study and a retrospective clinical analysis where patients underwent 18F-FDG PET/CT in both PET systems. The body phantom of the NEMA IEC with 10–37 mm diameter spheres were filled with an 18F-FDG solution. The root mean square error (RMSE) of SUV, the detectability of 10-mm sphere, NECphantom, the background variability (N10mm) and the contrast-noise-ratio (QH,10 mm/N10mm) were calculated based on the phantom analysis. We also examined the quality of the acquired clinical images using the NECpatient, NECdensity, SNRliver, SUVliver and SUVlesion. In the phantom study on Vision scanner, RMSE was relatively lower when the iteration number was 2, 3 or 4. To satisfy a visual score of 1.5 and the reference range of QH,10 mm/N10mm, a 60-s or longer acquisition was required. Our clinical findings show that NECpatient averaged 17.4 ± 1.72 Mcounts/m in mCT and 29.1 ± 2.83 Mcounts/m in Vision. Furthermore, NECdensity averaged 0.29 ± 0.05 kcounts/cm3 in mCT and 0.53 ± 0.09 kcounts/cm3 in Vision, respectively, whereas SNRliver averaged 14.6 ± 3.77% in mCT and 21.3 ± 1.69% in Vision (P = 0.0156), respectively. Finally, SUVliver averaged 2.82 ± 0.28 and 2.55 ± 0.30, SUVlesion ranged 1.6–17.6 and 1.9–22.9 in mCT and Vision, respectively. SiPM-PET/CT provides superior image quality and quantification accuracy compared to PMT-PET/CT. |
| Databáze: | OpenAIRE |
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