Relationship between oestrogen-receptor content and histological grade in human primary breast tumours
| Autor: | Keith Griffiths, C.W. Elston, R.W. Blamey, P V Maynard, C J Davies, J Johnson |
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| Rok vydání: | 1978 |
| Předmět: |
Adult
Oncology Cancer Research medicine.medical_specialty Lung Neoplasms medicine.medical_treatment Population Bone Neoplasms Breast Neoplasms Disease Breast cancer Internal medicine medicine Humans Endocrine system Neoplasm Metastasis education Mastectomy Aged education.field_of_study business.industry Cancer Middle Aged Prognosis medicine.disease Menopause Cell Transformation Neoplastic Receptors Estrogen Hormone receptor Female Lymph Nodes Neoplasm Recurrence Local business Research Article |
| Zdroj: | British Journal of Cancer |
| ISSN: | 1532-1827 0007-0920 |
| DOI: | 10.1038/bjc.1978.282 |
| Popis: | A series of 300 patients presenting consecutively with primary operable breast cancer has been studied. A significant correlation was found between oestrogen-receptor (ER) content and histological grade: the better-differentiated tumours rarely lacked receptor. This correlation was significant only in women defined as post-menopausal. Data on early recurrence of disease indicate a worse prognosis for women in whom primary tumours are ER-. |
| Databáze: | OpenAIRE |
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