Encapsulating Peritoneal Sclerosis Presenting after Two Donor Kidney Transplantations: A Case Report and Literature Review

Autor:	Sasmit Roy, Kenneth A. Bodziak, Monzurul Hasan Chowdhury, Vijay K. Vanguri, Kyrstin Alexander
Rok vydání:	2021
Předmět:	medicine.medical_specialty Abdominal pain Exploratory laparotomy business.industry medicine.medical_treatment Single Case Peritoneal dialysis Encapsulating peritoneal sclerosis medicine.disease Diseases of the genitourinary system. Urology Surgery End stage renal disease Kidney transplantation Bowel obstruction Transplantation Tamoxifen End-stage renal disease Nephrology medicine RC870-923 medicine.symptom Complication business
Zdroj:	Case Reports in Nephrology and Dialysis Case Reports in Nephrology and Dialysis, Vol 11, Iss 2, Pp 204-209 (2021)
ISSN:	2296-9705
Popis:	Encapsulating peritoneal sclerosis is a rare, recurring complication in peritoneal dialysis (PD) patients. With a mortality rate of 51%, it continues to be a therapeutic enigma among clinicians. However, the incidence after kidney transplantation (KT) has rarely been reported. We report a unique case of encapsulating peritoneal sclerosis (EPS), occurring years after failed initial living KT, and diagnosed after second deceased donor kidney transplantation. A 35-year-old male, on prior PD for 4 years, followed by failed KT of 8 years, was presented with abdominal pain, weight loss, and vomiting, 7 months after his second deceased donor KT. An abdominal computed tomography showed intra-abdominal loculated fluid collection, but no obstruction. Exploratory laparotomy revealed extensive peritoneal thickening and blocked intestinal loops. Histopathology was indicative of EPS with fibrous adhesions and sclerotic tissues. Besides restarting his immunosuppressive medications, tamoxifen therapy was initiated as definitive medical management. Currently, he is in clinical remission, follows at transplant clinic, and still experiences episodes of small bowel obstruction. Though the incidence of EPS after KT has been observed sporadically worldwide, none has been reported in the USA. Despite its prevalence in PD patients, therapeutic interventions attempted so far, are not definitive.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe0018aa9cc36565a40b1cafc4806c5 https://doi.org/10.1159/000514062 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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