Iridium-Stabilized π-Selenocyclohexadienyls: Synthesis, Molecular Structure, and Cytotoxicity
| Autor: | Tina Riedel, Julien Dubarle-Offner, Geoffrey Gontard, Laetitia Peyroux, Hani Amouri, Paul J. Dyson, Jean-Philippe Tranchier |
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| Přispěvatelé: | Architectures Moléculaires (A.R.C), Institut Parisien de Chimie Moléculaire (IPCM), Institut de Chimie du CNRS (INC)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie du CNRS (INC)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Institut des Sciences et Ingénierie Chimiques (ISIC), Ecole Polytechnique Fédérale de Lausanne (EPFL), Institut des Sciences et Ingénierie Chimiques, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Diffraction
010405 organic chemistry Organic Chemistry chemistry.chemical_element 010402 general chemistry 01 natural sciences 0104 chemical sciences Crystallography Microcrystalline chemistry Halogen Moiety Molecule [CHIM]Chemical Sciences Iridium Cytotoxicity Selenium ComputingMilieux_MISCELLANEOUS |
| Zdroj: | Synlett Synlett, 2015, 26 (11), pp.1563--1566. ⟨10.1055/s-0034-1378838⟩ SYNLETT SYNLETT, 2015, 26 (11), pp.1563--1566. ⟨10.1055/s-0034-1378838⟩ |
| ISSN: | 0936-5214 1437-2096 |
| Popis: | A series of iridium-stabilized selenocyclohexadienyls of general formula [Cp*Ir(η5-C6H5–nMenSe)][BF4] {Cp* = η5-C5Me5, n = 0, n = 1, and n = 3} is described, with the selenocyclohexadienyl unit being isolated for the first time by π-coordination to a Cp*Ir moiety. The solid-state structure of one of [Cp*Ir(η5-C6H2Me3Se)][BF4] was determined by single-crystal X-ray diffraction analysis. These compounds are obtained in good yields as orange-red microcrystalline solids by halogen displacement from the related π-bonded arene-chlorinated starting materials using Na2Se as the selenium source. Furthermore, these new compounds display relevant cytotoxic properties towards human ovarian cancer cells. |
| Databáze: | OpenAIRE |
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