An improved qEEG index for asymmetry detection during the Wada test
| Autor: | Guy Bogaarts, Jos P. H. Reulen, Danny M. W. Hilkman, Vivianne van Kranen-Mastenbroek, Erik D. Gommer |
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| Přispěvatelé: | MUMC+: HZC Niet Med Staf Klinische Neurofys (9), MUMC+: HZC Med Staf Spec Klinische Neurofys (9), RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Wilcoxon signed-rank test media_common.quotation_subject Electroencephalography Neuromonitoring Asymmetry Functional Laterality Lateralization of brain function 030218 nuclear medicine & medical imaging Young Adult 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Epilepsy surgery Eeg data Memory medicine Humans Electrodes Language Monitoring Physiologic media_common Epilepsy medicine.diagnostic_test business.industry Brain Pattern recognition Middle Aged Quantitative electroencephalography Neurology Wada test Female Intracarotid amobarbital procedure Neurology (clinical) Artificial intelligence Psychology business Neuroscience Brain symmetry index 030217 neurology & neurosurgery |
| Zdroj: | Epilepsy & Behavior, 62, 40-46. Elsevier Science |
| ISSN: | 1525-5050 |
| DOI: | 10.1016/j.yebeh.2016.06.009 |
| Popis: | The Wada test is commonly used to evaluate language and memory lateralization in candidates for epilepsy surgery. The spatial Brain Symmetry Index (BSI) quantifies inter-hemispheric differences in the EEG. Its application has been shown to be feasible during Wada testing. We developed a method for the quantification of EEG asymmetry that matches visual assessments of the EEG better than BSI. Fifty-three patients' EEG data, with a total of 85 injections were analyzed. In a step-wise, data-driven manner, multiple electrode and frequency band combinations were evaluated. Eventually, BSI, calculated using only the frontal electrodes F 3 and F 4 , was combined with a temporal measure of delta power in the central electrodes, C 3 and C 4 , into a new measure: cBSI. Using the area under the ROC curve (AUC), we showed that cBSI performs significantly better relative to BSI (median AUC 0.98 versus 0.96, p = 0.0015, Wilcoxon signed rank test). Our results showed that asymmetry detection was significantly improved by combining temporal with spatial qEEG measures. In the future, our combined qEEG measure could allow for a more objective way of monitoring EEG asymmetry, thereby increasing the feasibility of using EEG as a monitoring tool during the Wada test. Future studies should, however, validate our cBSI method in real time in the operating room or radiology suite. |
| Databáze: | OpenAIRE |
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