Antenatal blood transfusion in South Africa: indications and practice in a high-HIV-prevalence setting
| Autor: | John Anthony, Edward L. Murphy, Lauren Courtney, Adam Jauregui, Joan F. Hilton, Robert Crookes, Charlotte Ingram, Jennifer Hull, Nhlbi Reds-Iii South Africa Program, Nareg Roubinian, Randolph Green-Thompson, S Fawcus, Evan M. Bloch |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Blood transfusion Cross-sectional study Anemia medicine.medical_treatment Immunology Gestational Age HIV Infections Hemorrhage 030204 cardiovascular system & hematology Abortion 03 medical and health sciences South Africa 0302 clinical medicine Pregnancy Epidemiology medicine Prevalence Immunology and Allergy Humans Blood Transfusion Ectopic pregnancy business.industry Obstetrics Gestational age Transfusion Reaction Hematology medicine.disease Cross-Sectional Studies Female business 030215 immunology |
| Zdroj: | TransfusionREFERENCES. 60(3) |
| ISSN: | 1537-2995 |
| Popis: | BACKGROUND Globally, data on antenatal blood transfusion practices are scarce. We sought to characterize the epidemiology of antenatal transfusion in South Africa. STUDY DESIGN AND METHODS A cross-sectional study was conducted of women who were transfused during pregnancy (>48 hr before anticipated delivery) at two hospitals in Durban and Soweto in 2014 to 2015. Medical record data on demographics, obstetric history, anemia, HIV status, and indications for blood transfusion were abstracted. RESULTS The records on a total of 560 transfused pregnant women were evaluated; mean age was 28 years, 98% were of black African ethnicity, and 28% were HIV positive. At time of transfusion, one-half were in the first trimester. Hemorrhage was noted in 76% of women, most of which was associated with abortion (67%) or ectopic pregnancy (27%). Most women were transfused with red blood cells (RBCs; median, 2 units); 14% of women were transfused with plasma and 2% with platelets. Median pre- and posttransfusion hemoglobin levels were 6.9 g/dL and 9.2 g/dL, respectively; the latter differed by hospital (8.7 g/dL vs. 9.5 g/dL; p |
| Databáze: | OpenAIRE |
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