Circadian rhythm in negative affect: Implications for mood disorders
Autor: | Alec M. Berman, Maya X. Herzig, Nicole P. Bowles, Andrew W. McHill, Steven Shea, Noal A. Clemons, Sally A. Roberts, Matthew P. Butler, Miki Morimoto, Saurabh S. Thosar, Jonathan S. Emens |
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Rok vydání: | 2020 |
Předmět: |
Male
Physiology Endogeny Nocturnal Article 03 medical and health sciences 0302 clinical medicine Sleep Disorders Circadian Rhythm mental disorders medicine Insomnia Humans Circadian rhythm Wakefulness Biological Psychiatry business.industry Mood Disorders Middle Aged medicine.disease Actigraphy 030227 psychiatry Circadian Rhythm Psychiatry and Mental health Affect Mood Mood disorders Major depressive disorder Female medicine.symptom business Sleep 030217 neurology & neurosurgery |
Zdroj: | Psychiatry Res |
ISSN: | 1872-7123 |
Popis: | In humans, there is an endogenous, near 24-h (i.e., circadian) variation in mood with the best mood occurring during the circadian day and the worst mood occurring during the circadian night. Only positive affect, and not negative affect, has been shown to contribute to this circadian rhythm. We discovered a sharp circadian peak in negative affect during the circadian night coincident with a circadian trough in positive affect. These findings may help explain the association of depression with insomnia, the increased risk of suicide with nocturnal wakefulness, and the correlation between circadian misalignment and symptom severity in Major Depressive Disorder. |
Databáze: | OpenAIRE |
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