Supplementary Figures 1-5 from Inhibiting Integrin β8 to Differentiate and Radiosensitize Glioblastoma-Initiating Cells

Autor: Anthony Lemarié, Christine Toulas, Elizabeth Cohen-Jonathan Moyal, Aline Kowalski-Chauvel, Solène Evrard, Aurore Siegfried, Thomas Filleron, Julia Gilhodes, Dina Ferreira Da Mota, Vincent Lubrano, Pauline Deshors, Sabrina Boyrie, Perrine Dahan, Florent Arnauduc, Caroline Delmas, Sylvie Monferran, Laure Malric
Rok vydání: 2023
DOI: 10.1158/1541-7786.22516246
Popis: S1. Phenotypic characterization of GIC-enriched neurospheres and related GDC cultures. S2. Expression of major integrins in GIC compared to GDC. S3. Correlation of ITGB8 and stem/differentiated markers in GB patients from the TCGA database. S4. Immunohistological pattern of ITGβ8 and Sox2 staining. S5. siRNA-mediated ITGβ8 knock-down impairs GIC stemness and induces apoptosis.
Databáze: OpenAIRE