Two cases of subcutaneous Scedosporium apiospermum infection treated with voriconazole
| Autor: | Paul E. Verweij, W.G.J. Melchers, F. Bosma, Andreas Voss, J. Biert, R.G.L. de Sevaux, B.J. Kullberg, H.W. van Hamersvelt |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Antifungal
Microbiology (medical) Male Antifungal Agents medicine.drug_class Intrinsic resistance Biology Microbiology Opportunistic pathogen Effective Primary Care and Public Health [EBP 3] medicine voriconazole Allescheria boydii Humans Scedosporium Pathogen Aged Voriconazole Aged 80 and over Scedosporium apiospermum General Medicine Middle Aged Triazoles DNA Fingerprinting RAPD Renal disorders [UMCN 5.4] Infectious Diseases Pyrimidines fingerprinting Mycetoma Microbial pathogenesis and host defense [UMCN 4.1] medicine.drug |
| Zdroj: | Clinical Microbiology and Infection, 9, 7, pp. 750-3 Clinical Microbiology and Infection, 9, 750-3 |
| ISSN: | 1198-743X |
| Popis: | Item does not contain fulltext Scedosporium apiospermum is a mold that is increasingly being recognized as an opportunistic pathogen in immunocompromised patients, and treatment is complicated by intrinsic resistance to several antifungal agents. In our hospital, two cases of S. apiospermum infection occurring within 2 weeks were successfully treated with voriconazole. Since both patients were infected with an uncommon pathogen, a search for a common nosocomial source was performed. As environmental cultures yielded no S. apiospermum, and random amplified polymorphic DNA (RAPD) fingerprinting showed that the patients' strains were genotypically unrelated, we considered a common nosocomial source of S. apiospermum to be unlikely. |
| Databáze: | OpenAIRE |
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