Stage T1 glottic carcinoma: results of radiation therapy or laser excision
| Autor: | B E Epstein, Michael E. Johns, Ding-Jen Lee, Haskins K. Kashima |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Male
Glottis medicine.medical_specialty Voice Quality business.industry medicine.medical_treatment Rate control Salvage therapy Middle Aged Stage t1 Surgery Radiation therapy medicine.anatomical_structure Glottic cancer medicine Retrospective analysis Humans Female Radiology Nuclear Medicine and imaging In patient Laser Therapy business Laryngeal Neoplasms |
| Zdroj: | Radiology. 175:567-570 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/radiology.175.2.2326483 |
| Popis: | A retrospective analysis was made of the data on 60 patients with stage T1 glottic carcinoma (43 T1a, 17 T1b) who received radiation therapy and 17 patients with T1a disease who underwent laser excision as the primary treatment modality. Patients who received radiation therapy achieved 3- and 5-year actuarial local control rates of 92% and 89% for T1a and 77% and 77% for T1b disease, respectively. In patients who underwent laser excision (all with T1a disease), the 3-year local control rate was 77%. Of the 42 evaluable irradiated T1a patients, 31 (74%) had a normal to near-normal voice, eight (19%) had mild or intermittent hoarseness, and three (7%) had persistent hoarseness. Of the 13 evaluable patients in the laser-excision group, four (31%) had a normal to near-normal voice, five (38%) had mild or intermittent hoarseness, and four (31%) had persistent hoarseness. The difference in the quality of voice between these two groups is statistically significant (P = .012), although the ultimate local control rate after salvage therapy for irradiated patients (97%) was similar to that for laser-excision patients (94%). |
| Databáze: | OpenAIRE |
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