Vestibular-evoked myogenic potentials in patients with large vestibular aqueduct syndrome
| Autor: | Yan Zhang, Junli Wang, Yuzhong Zhang, Qing Zhang, Zichen Chen, Min Xu, Juan Hu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Vestibular aqueduct Adolescent Vestibular evoked myogenic potential Audiology Sensitivity and Specificity Vestibular Aqueduct Young Adult 03 medical and health sciences 0302 clinical medicine Vertigo Statistical significance medicine Humans In patient Child 030223 otorhinolaryngology Cervical Vestibular Evoked Myogenic Potentials Vestibular system biology Adult patients business.industry Age Factors Syndrome General Medicine biology.organism_classification Vestibular Evoked Myogenic Potentials medicine.anatomical_structure Vestibular Diseases Otorhinolaryngology Case-Control Studies Child Preschool 030220 oncology & carcinogenesis Female business |
| Zdroj: | Acta Oto-Laryngologica. 140:40-45 |
| ISSN: | 1651-2251 0001-6489 |
| Popis: | Background: The vestibular function in patients of large vestibular aqueduct syndrome (LVAS) has not been clarified yet.Aims/objectives: To investigate the characteristic of otolithic organ in LVAS patients, we accessed their ocular and cervical vestibular evoked myogenic potentials (oVEMPs and cVEMPs).Material and methods: This study was carried out between 29 bilateral LVAS patients and 35 healthy controls. Parameters of VEMPs were analyzed.Result: In children patients, response rate for oVEMP was 93.47% and 86.95% for cVEMP. No statistical significance was found compared to their controls. In adult patients, response rate for oVEMP was 83.33% and 75% for cVEMP, which were statistically lower than their controls. In comparison to parameters of VEMPs, no statistical significance were found in children group. Amplitude of oVEMP was significantly higher and that of cVEMP was lower in LVAS adults. N1 latencies were significantly longer and P1 latencies were shorter in adult patients than in controls of cVEMP. Thresholds and N1-P1 intervals of VEMP were found no statistical significance in adult group.Conclusions and significance: We discovered a severer otolithic dysfunction in adults than in children patients. We recommend cVEMP a more effective and sensitive method than oVEMP in assessment of LAVS adult patients. |
| Databáze: | OpenAIRE |
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