Exercise performance after standard rehabilitation in COPD patients with lung hyperinflation

Autor: Enrico Clini, Guido Vagheggini, Ernesto Crisafulli, Franco Pasqua, Elena Venturelli, Andrea Iattoni, Gianluca Biscione, Alfredo Cesario, Sasha Lucic, Nicolino Ambrosino
Rok vydání: 2011
Předmět:
Zdroj: Internal and Emergency Medicine. 9:23-31
ISSN: 1970-9366
1828-0447
DOI: 10.1007/s11739-011-0727-z
Popis: The role of pulmonary rehabilitation (PR) in COPD patients with lung hyperinflation has not yet been fully investigated. We retrospectively evaluated the effect of a standard PR course on exercise tolerance and symptoms according to the presence or absence of associated lung hyperinflation, as defined by lung function parameters in three Italian rehabilitation centres. In a cohort of 823 COPD patients (age 71 ± 8 years, FEV1 56 ± 18% pred.) we have systematically recorded: changes (∆) in 6-minute walking test (6MWD) as the primary outcome; dyspnoea (D); muscle fatigue (F); SO2nadir during effort; perceived breathlessness score (MRC); and specific health-related quality of life (SGRQ). Outcomes were compared between patients with lung hyperinflation (n = 283, LH) or without (n = 540 No-LH). Groups were comparable for age, body mass index, baseline exercise tolerance, and breathlessness. ∆-6MWD (+72 ± 47 vs. +62 ± 42 m, p
Databáze: OpenAIRE