Longitudinal Comparison of Sexual Function After 3-Dimensional Conformal Radiation Therapy or Prostate Brachytherapy

Autor: Dan Theodorescu, Christopher T. Chen, Richard K. Valicenti, Eric A. Bissonette
Rok vydání: 2002
Předmět:
Zdroj: Journal of Urology. 168:2499-2504
ISSN: 1527-3792
0022-5347
DOI: 10.1016/s0022-5347(05)64177-8
Popis: Purpose: The risk of erectile dysfunction can influence treatment decisions for localized prostate cancer. To estimate the risk from 2 popular radiotherapies we compared erectile function and overall satisfaction with sexual function after 3-dimensional (D) conformal radiation therapy and transperineal prostate brachytherapy.Materials and Methods: A total of 128 patients with prostate cancer underwent 3-D conformal radiation therapy (median dose 70.2 Gy. to the planning target volume) and 60 underwent 103palladium transperineal prostate brachytherapy (median dose 90 or 115 Gy. to 80% of the prostate with or without external nonconformal beam radiation therapy. Of the 128 patients 47 (37%) also received a luteinizing hormone releasing hormone (LH-RH) agonist (3 to 4 months), whereas 26 (43%) of the 60 patients received external beam radiation therapy and LH-RH (8 to 9 months). We evaluated erectile function and overall satisfaction with questions from validated, self-administered questionnaires. Pa...
Databáze: OpenAIRE