White cell function in Down's syndrome
| Autor: | Christine Costello, Anne Webber |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Neutrophils Nitroblue tetrazolium Phagocytosis Internal medicine Candida albicans Genetics medicine Humans Child Leucocyte alkaline phosphatase Genetics (clinical) S syndrome biology Nitroblue Tetrazolium Phagocytic index Middle Aged Alkaline Phosphatase biology.organism_classification In vitro Endocrinology Peroxidases Immunology Female Down Syndrome Function (biology) |
| Zdroj: | Clinical Genetics. 9:603-605 |
| ISSN: | 1399-0004 0009-9163 |
| DOI: | 10.1111/j.1399-0004.1976.tb01619.x |
| Popis: | Neutrophil function was studied in 25 patients with Down's syndrome at a mental subnor-mality hospital and compared with 26 normal controls. In vitro killing of Candida albicans was significantly lower in the Down's group, but there was no difference in the percentage of cells actively involved in phagocytosis or in the phagocytic index. The spontaneous nitroblue tetrazolium reduction was increased in 10 patients, but no abnormality of pero-xidase activity or leucocyte alkaline phosphatase activity was found. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text