Harnessing an emissive guanine surrogate to design small-molecule fluorescent chemosensors of O6-methylguanine-DNA-methyltransferase (MGMT)

Autor:	Alexandra Fillion, Jaime Franco Pinto, Anton Granzhan
Rok vydání:	2022
Předmět:	Organic Chemistry Physical and Theoretical Chemistry Biochemistry
Zdroj:	Organic & Biomolecular Chemistry. 20:1888-1892
ISSN:	1477-0539 1477-0520
DOI:	10.1039/d2ob00208f
Popis:	Activity of O6-methylguanine-DNA-methyltransferase (MGMT) can be monitored in real time using chemosensors that generate an emissive guanine analogue thienoguanine (thGN).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb82acf467dfd486f4c13025bcff436 https://doi.org/10.1039/d2ob00208f Zobrazit plný text záznamu