| Autor: |
Mmolawa, L., Siwelana, T., Hanrahan, C. F., Lebina, L., Martinson, N. A., Dowdy, D., Nonyane, B. A. S. |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Int J Tuberc Lung Dis |
| ISSN: |
1027-3719 |
| Popis: |
BACKGROUND: Early presentation to healthcare facilities is critical for early diagnosis and treatment of TB. We studied self-reported time to care-seeking from the onset of TB symptoms among primary healthcare clinic (PHC) attendees in Limpopo Province, South Africa.METHODS: We used data from participants enrolled in a cluster-randomized trial of TB case finding in 56 PHC clinics across two health districts. We fitted log-normal accelerated failure time regression models and we present time ratios (TRs) for potential risk factors.RESULTS: We included 2,160 participants. Among the 1,757 (81%) diagnosed with active TB, the median time to care-seeking was 30 days (IQR 14–60); adults sought care later than children/adolescents (adjusted TR aTR 1.47, 95% CI 1.10–1.96). Among those not diagnosed with TB, the median was 14 days (IQR 7–60); being HIV-positive (aTR 1.57, 95% CI 1.03–2.40); having less than grade 8 education and currently smoking were associated with longer time to care-seeking. In the combined analysis, living with HIV and having underlying active TB was associated with faster care-seeking (TB status x HIV interaction: TR 0.68, 95% CI 0.48–0.96).CONCLUSION: Delay in care-seeking was associated with age, lower education and being a current smoker. TB awareness campaigns targeting these population groups may improve care-seeking behavior and reduce community TB transmission. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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