Comprehensive assessment of nutritional status and nutritional-related complications in newly diagnosed esophageal cancer patients: A cross-sectional study
| Autor: | Majid Ghayour-Mobarhan, Fatemeh Varshoee Tabrizi, Sara Movahed, Amir Hossein Alavi, Mahtab Salek, Naseh Pahlavani, Pegah Zabeti, Mohsen Nematy, Maryam Emadzadeh, Gordon A. Ferns, Saeid Eslami, Abdolreza Norouzy, Majid Khadem-Rezaiyan, Ali Ghanbari Motlagh, Mehdi Seilanian Toussi |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Constipation Esophageal Neoplasms Cross-sectional study Digestive System Diseases Nutritional Status 030209 endocrinology & metabolism Critical Care and Intensive Care Medicine 03 medical and health sciences 0302 clinical medicine Weight loss Internal medicine Weight Loss Prevalence medicine Humans Aged Aged 80 and over 030109 nutrition & dietetics Nutrition and Dietetics Esophageal Pain business.industry Malnutrition Middle Aged Anthropometry Esophageal cancer medicine.disease Cross-Sectional Studies Social Class Female Dietary Proteins Nutrition Therapy medicine.symptom Underweight Energy Intake business |
| Zdroj: | Clinical Nutrition. 40:4449-4455 |
| ISSN: | 0261-5614 |
| DOI: | 10.1016/j.clnu.2021.01.003 |
| Popis: | Summary Background & aims Malnutrition is prevalent in upper gastrointestinal cancer patients. The purpose of this study was a comprehensive assessment of nutritional status in newly diagnosed patients with esophageal cancer. Methods Newly diagnosed esophageal cancer patients were referred to a chemo-radiation referral center in Mashhad, Iran, between February 2017 to February 2019. Anthropometric indices, a Patient-Generated Subjective Global Assessment (PG-SGA) tool, body composition, dietary intake, nutritional-related complications, and laboratory tests were assessed. Results One hundred and eighty-nine patients with a mean age of 67.1 ± 12 and a male to female ratio of 98 to 91 were included. Ninety-seven (51.3%) of patients had experienced significant weight loss and 56 (29.6%) were underweight at diagnosis. According to PG-SGA, 179 (94.7%) needed nutritional interventions. Reduced muscle mass and low handgrip strength were observed in 70 (39.4%) and 26 (14.4%) of patients, respectively. Inadequate intakes of energy (less than 24 kcal/kg/day) and protein (less than 1.2 g/kg/day) were found in 146 (77.8%) and 171 (91%) patients, respectively. The mean total daily energy and protein intakes of subjects were 943.8 ± 540 kcal/day, and 30.6 ± 21 g/day, respectively. The most common nutritional-related complications were as follows: dysphagia (84.8%), anorexia (31.6%), constipation (62.1%), esophageal pain (48.4%), and dyspepsia (41.1%). Conclusion Our study demonstrated a high prevalence of malnutrition in newly diagnosed esophageal cancer patients. This fact demonstrates the importance of early screening of nutritional status via PG-SGA tool, clinical evaluation, dietary intake evaluations, and laboratory tests, based on which effective nutritional interventions and Symptoms management may be introduced in these patients. |
| Databáze: | OpenAIRE |
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