Association between risk factors and glaucomatous damage in untreated primary open-angle glaucoma
| Autor: | K. Gugleta, Natalie Portmann, Selim Orgül, Josef Flammer, Anna Polunina, Nicolas Philipp Waldmann, Robert Katamay, A. Kochkorov |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Retinal Ganglion Cells medicine.medical_specialty Intraocular pressure genetic structures Open angle glaucoma Optic Disk Nerve fiber layer Glaucoma chemistry.chemical_compound Retinal Diseases Risk Factors Ophthalmology Heart rate medicine Humans Intraocular Pressure business.industry Retinal Laser Doppler velocimetry Middle Aged medicine.disease eye diseases medicine.anatomical_structure chemistry Female sense organs business Perfusion Glaucoma Open-Angle Tomography Optical Coherence Follow-Up Studies |
| Zdroj: | Journal of glaucoma. 22(6) |
| ISSN: | 1536-481X |
| Popis: | PURPOSE To analyze an association between the presumed risk factors for glaucoma and the actual extent of glaucomatous damage in untreated primary open-angle glaucoma. PATIENTS AND METHODS In 50 untreated open-angle glaucoma patients, we analyzed an association between the level of glaucomatous damage and presumed glaucoma risk factors: mean untreated intraocular pressure (IOP) and short-term IOP variability, ocular pulse amplitude, corneal thickness, acral and corneal temperature, retinal arterial diameter and retinal venous diameter, choroidal blood flow (laser Doppler flowmetry flow, velocity, volume), heart rate, and ocular perfusion pressure. Morphologic damage (mean retinal nerve fiber layer thickness, measured by ocular coherence tomography) and functional damage (visual field mean defect) were evaluated separately in 2 forward-stepwise multiple regression models. RESULTS The mean retinal nerve fiber layer thickness was significantly (P |
| Databáze: | OpenAIRE |
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