Idiopathic infantile hypercalcaemia--a continuing enigma
| Autor: | G. J. A. I. Snodgrass, Robert D. Cohen, N. D. T. Martin |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Hypercalcaemia Arterial Occlusive Diseases Growth Pulmonary Artery 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Intellectual Disability Intellectual disability medicine Humans Child Kyphoscoliosis business.industry Incidence (epidemiology) Hyperacusis nutritional and metabolic diseases Aortic Valve Stenosis Feeding Behavior Syndrome medicine.disease Obesity 3. Good health Surgery Failure to Thrive Facial Expression Pediatrics Perinatology and Child Health Failure to thrive Etiology Hypercalcemia Female medicine.symptom business 030217 neurology & neurosurgery Research Article |
| Zdroj: | Archives of disease in childhood. 59(7) |
| ISSN: | 1468-2044 |
| Popis: | Seventy six children with documented Fanconi-type idiopathic infantile hypercalcaemia were studied and compared with 41 with the Williams-Beuren syndrome. Clinical comparison showed, as expected, very close similarities but also considerable differences, particularly in the severity of feeding problems and the degree of failure to thrive. The estimated incidence of idiopathic infantile hypercalcaemia alone has remained constant for the past 20 years, at approximately 18 cases per year in the United Kingdom (1 per 47 000 total live births). Long term morbidity in these children is mainly due to mental handicap and arteriopathy, but hypertension (29%), kyphoscoliosis (19%), hyperacusis (75%), and obesity (50%) may be added complications. In one child, hypercalcaemia recurred during adolescence but this seems to be excessively rare. More detailed investigation before treatment is required to discover the aetiology of hypercalcaemia in this condition. |
| Databáze: | OpenAIRE |
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