Optical coherence tomography system requirements for clinical diagnostic middle ear imaging
Autor: | Manohar Bance, Robert B. A. Adamson, Dan MacDougall, Jeremy Brown, James W. Rainsbury |
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Rok vydání: | 2015 |
Předmět: |
medicine.medical_specialty
Image quality Biomedical Engineering Ear Middle Pilot Projects Audiology Sensitivity and Specificity Biomaterials Imaging Three-Dimensional Optical coherence tomography Otology Cadaver medicine Humans medicine.diagnostic_test Ossicles business.industry 3d image processing Reproducibility of Results Equipment Design Image Enhancement Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials Equipment Failure Analysis System requirements medicine.anatomical_structure Middle ear sense organs Tomography business Tomography Optical Coherence Biomedical engineering |
Zdroj: | Journal of Biomedical Optics. 20:056008 |
ISSN: | 1083-3668 |
Popis: | Noninvasive middle ear imaging using optical coherence tomography (OCT) presents some unique challenges for real-time, clinical use in humans. We present results from a two-dimensional/three-dimensional OCT system built to assess the imaging requirements of clinical middle ear imaging, and the technical challenges associated with them. These include the need to work at a low numerical aperture, the deleterious effects of transtympanic imaging on image quality at the ossicles, sensitivity requirements for clinical fidelity of images at real-time rates, and the high dynamic-range requirements of the ear. We validated the system by imaging cadaveric specimens with simulated disorders to show the clinical applicability of the images. We also provide additional insight into the likely role of OCT in clinical otology. |
Databáze: | OpenAIRE |
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