Relationship of human follicular diameter with oocyte fertilization and development after in-vitro fertilization or intracytoplasmic sperm injection
| Autor: | Robert Schoysman, M. Nijs, F. Ectors, J. Van Hoeck, G. Verhaegen, A Delvigne, Fernand Leroy, Pierre Vanderzwalmen |
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| Rok vydání: | 1997 |
| Předmět: |
Male
Microinjections medicine.medical_treatment Fertilization in Vitro Biology Intracytoplasmic sperm injection Andrology Embryonic and Fetal Development Human fertilization Ovarian Follicle Follicular phase medicine Humans Ovarian follicle Cell Size In vitro fertilisation Rehabilitation Obstetrics and Gynecology Embryo Mammalian Oocyte Follicular fluid Follicular Fluid medicine.anatomical_structure Reproductive Medicine Oocytes Female Folliculogenesis |
| Zdroj: | Human Reproduction. 12:2002-2005 |
| ISSN: | 1460-2350 0268-1161 |
| DOI: | 10.1093/humrep/12.9.2002 |
| Popis: | The aim of this work was to evaluate the relationship between follicular size at the time of oocyte retrieval, and the subsequent oocyte competence to be fertilized and to develop in vitro. All the obtained oocytes were classified according to the corresponding volume of aspirated follicular fluid. Aspirated volume of follicular fluid2 ml corresponded to a follicular diameter16 mm and constituted the small size group. Volume of follicular fluid from 2 to 6 ml corresponded to a diameter from 16 to 23 mm and constituted the medium size group. The large size group contained follicles with diameter23 mm and corresponded to an aspirated volume of follicular fluid of6 ml. A progressive and significant increase in the rates of oocytes with a first polar body was observed from the small size group to the other groups and from the medium to the large size group: 75.3, 85.9 and 95.3% respectively. After classical in-vitro fertilization (IVF), significantly better rates of fertilization and development were obtained in the medium size group compared to the two other groups. Moreover, a positive relationship was observed between follicular diameter and rates of embryos scored as 'good' when oocytes were fertilized by intracytoplasmic sperm injection (ICSI). These results demonstrated that follicular size is positively related to the oocyte ability to be fertilized and to develop. Although oocytes from small follicles gave lower percentages of development probably due to partial oocyte incompetence, they allowed an increase in the total number of embryos scored as 'good'. |
| Databáze: | OpenAIRE |
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