Renal hemodynamic changes during long-term antihypertensive therapy
| Autor: | John A. Mitas, Sanford E. Warren, Irving M. Cohen, Daniel T. O'Connor |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
medicine.medical_specialty
Mean arterial pressure Time Factors Blood Pressure Propranolol Kidney Essential hypertension law.invention Hydrochlorothiazide law Internal medicine medicine Humans Pharmacology (medical) Antihypertensive Agents Pharmacology Clinical pharmacology business.industry Hemodynamics Furosemide Middle Aged medicine.disease Clonidine Hypertension Cardiology Kallikreins Guanabenz business Glomerular Filtration Rate medicine.drug |
| Zdroj: | Clinical Pharmacology and Therapeutics. 29:310-317 |
| ISSN: | 1532-6535 0009-9236 |
| Popis: | Studies of renal hemodynamics were carried out in 84 patients with essential hypertension during long-term antihypertensive therapy with a number of drugs. Renal perfusion was maintained or enhanced despite a fall in mean arterial pressure during therapy with hydrochlorothiazide, furosemide, clonidine, prazosin, and the combination of guanabenz and hydrochlorothiazide. Renal perfusion deteriorated during long-term treatment with propranolol. Renal hemodynamics may be enhanced, maintained, or adversely influenced depending on the choice of antihypertensive agent. Clinical Pharmacology and Therapeutics (1981) 29, 310–317; doi:10.1038/clpt.1981.41 |
| Databáze: | OpenAIRE |
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