A processed gene coding for a sarcomeric actin in Xenopus laevis and Xenopus tropicalis
Autor: | G Spohr, F Stutz |
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Rok vydání: | 1987 |
Předmět: |
Sarcomeres
Transcription Genetic Xenopus Molecular Sequence Data General Biochemistry Genetics and Molecular Biology Xenopus laevis Myofibrils Species Specificity Gene expression medicine Animals Amino Acid Sequence Northern blot Molecular Biology Gene Peptide sequence Actin chemistry.chemical_classification Base Sequence General Immunology and Microbiology biology Muscles Myocardium General Neuroscience Skeletal muscle biology.organism_classification Molecular biology Actins Amino acid medicine.anatomical_structure Genes chemistry Oocytes Female Research Article |
Zdroj: | The EMBO Journal. 6:1989-1995 |
ISSN: | 0261-4189 |
DOI: | 10.1002/j.1460-2075.1987.tb02462.x |
Popis: | A processed gene potentially coding for a sarcomeric actin has been identified in Xenopus laevis and in the more primitive species X. tropicalis. The peptides encoded in these two species differ by two out of 377 amino acid residues. On the basis of the amino acid substitutions, the encoded peptide was identified as an alpha-skeletal actin in X. laevis and as an alpha-cardiac actin in X. tropicalis. Northern blot analysis and S1 mapping experiments suggest that in X. tropicalis the gene is expressed in embryos and adult heart. In X. laevis, transcripts homologous to this gene were found in embryos and in adult tissues, but predominantly in skeletal muscle rather than in heart. |
Databáze: | OpenAIRE |
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