Impact of Heated Humidified High Flow Air via Nasal Cannula on Respiratory Effort in Patients with Chronic Obstructive Pulmonary Disease
| Autor: | Charles W. Atwood, Nicholas J. Macmillan, Kathryn C. Little, Hobart Schweikert, Thomas L. Miller, Colleen Paul, Sharon Camhi |
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| Rok vydání: | 2017 |
| Předmět: |
Pulmonary and Respiratory Medicine
COPD Respiratory rate business.industry Dead space respiratory system 030204 cardiovascular system & hematology medicine.disease medicine.disease_cause respiratory tract diseases 03 medical and health sciences Work of breathing 0302 clinical medicine 030228 respiratory system Anesthesia Breathing Medicine Arterial blood business Nasal cannula Tidal volume Original Research |
| Zdroj: | Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation. 4:279-286 |
| ISSN: | 2372-952X |
| Popis: | Background: High flow nasal cannula therapy (HFNC) has been widely adopted for respiratory distress, and evidence suggests that purging dead space of the upper airway improves gas fractions in the lung. This study tests the hypothesis that HFNC with room air could be as effective as low flow oxygen in chronic obstructive pulmonary disease (COPD). Methods: Thirty-two COPD patients prescribed 1 - 2 L/min of oxygen were studied. The conditions tested consisted of a control (CTRL; no therapy), then in random order HFNC and prescribed low flow oxygen (LFO). HFNC was the highest flow tolerated up to 35 L/min without supplemental oxygen. Arterial blood gases (ABGs), respiratory rate (RR), heart rate (HR) and tidal volume (VT) were measured at the end of each condition. Results: Arterial oxygen (PaO2) was greater (p < 0.001) for LFO than both HFNC and CTRL (CTRL=57.4±6.1mmHg, HFNC=58.6±8.3mmHg, LFO=72.6±10.2mmHg). HFNC reduced RR by 11% (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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